It is a chronic inflammation of nose characterized by atrophy of the nasal mucosa.
Typically seen in females nearing puberty.
Aetiology:
- Hereditary
- Racial (more in whites)
- Endocrinal disturbances (oestrogen)
- Nutritional deficiency.
- Infections
- Auto-immune
Pathology:
Squamous metaplasia in the mucosa, atrophy of seromucinous glands, venous blood sinusoids and neve elements, obliterative endarteritis. Turbinates undergo resorption. Paranasal sinuses are small due to arrested development.
Clinical features:
- Anosmia
- Degenerative changes
- Nasal obstruction
- Epistaxis
- Greenish/greyish black dry crusts
- Typically, the posterior wall of the nasopharynx can be visualised.
- Nose may show saddle deformity
Treatment:
No definitive treatment is available for this condition. The following measures are tried to provide releif to the patient.
Medical
- Nasal irrigation and removal of crusts (alkaline solution)
- 25% glucose in glycerine
- Local antibiotics
- Oestradiol spray
- Placental extract
- Potassium iodide (oral)
Surgical
- Young's / Modified Young's operation - it involves the complete or partial closure of both the nostrils, to be opened after 6 months. This allows the turbinates and the mucosa to grow.
- Narrowing the nasal cavities - this is done by injection of teflon paste or insertion of fat/cartilage/bone/teflon strips under the mucoperiostium.
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