Sunday, September 7, 2008

Atrophic Rhinitis

Definition:
It is a chronic inflammation of nose characterized by atrophy of the nasal mucosa.
Typically seen in females nearing puberty.

Aetiology:
  1. Hereditary
  2. Racial (more in whites)
  3. Endocrinal disturbances (oestrogen)
  4. Nutritional deficiency.
  5. Infections
  6. Auto-immune
Pathology:
Squamous metaplasia in the mucosa, atrophy of seromucinous glands, venous blood sinusoids and neve elements, obliterative endarteritis. Turbinates undergo resorption. Paranasal sinuses are small due to arrested development.

Clinical features:
  1. Anosmia
  2. Degenerative changes
  3. Nasal obstruction
  4. Epistaxis
  5. Greenish/greyish black dry crusts
  6. Typically, the posterior wall of the nasopharynx can be visualised.
  7. Nose may show saddle deformity
Treatment:

No definitive treatment is available for this condition. The following measures are tried to provide releif to the patient.

Medical
  1. Nasal irrigation and removal of crusts (alkaline solution)
  2. 25% glucose in glycerine
  3. Local antibiotics
  4. Oestradiol spray
  5. Placental extract
  6. Potassium iodide (oral)
Surgical
  1. Young's / Modified Young's operation - it involves the complete or partial closure of both the nostrils, to be opened after 6 months. This allows the turbinates and the mucosa to grow.
  2. Narrowing the nasal cavities - this is done by injection of teflon paste or insertion of fat/cartilage/bone/teflon strips under the mucoperiostium.

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